Download The Black Book Research Report: 2026 State Of Healthcare Laboratory IT Solutions

Survey of 808 qualified LIS/LIMS users across U.S. hospital networks, reference labs, community facilities, and physician office labs. Laboratories are navigating a pivotal transition: entrenched legacy LIS platforms still anchor large, high-volume labs, but cloud-native and modular solutions are capturing momentum in community and specialty settings. Architecture is no longer a back-office choice—it is the determinant of interoperability, reimbursement resilience, and patient safety.

Black Book Research’s State of Healthcare Laboratory Information Technology 2025–2026 delivers the first vendor-agnostic benchmarking of LIS/LIMS platforms under today’s dual pressures: interoperability mandates (USCDI v3, TEFCA) and reimbursement volatility (PAMA, MolDX, SALSA). The report maps a fractured but rapidly evolving ecosystem of legacy cores, cloud entrants, and middleware bridges.

What You’ll Learn

Market Architecture in Flux

How EHR-centric modules, best-of-breed LIS, and cloud-forward platforms are scaling under regulatory and financial pressure

Discipline-Specific Informatics:

Chemistry, microbiology, genomics, digital pathology, transfusion medicine, and POCT all demand specialized IT approaches.

Revenue Cycle Under Stress:

Denials, Z-codes, and clearinghouse outages make LIS/RCM integration an enterprise risk, not a billing afterthought.

Interoperability Scoreboards

Black Book maturity rubric across terminology hygiene, transport portfolios, compendia governance, and TEFCA readiness.

Top Vendors by Category

From Clinisys and Epic in core LIS to Sectra in pathology, Velsera in genomics, and XIFIN in RCM, see who leads across 13 software domains.

2025–2030 Scenarios

Rail standardization, decentralized diagnostics, and digital pathology normalization—three plausible futures reshaping lab IT.

Fault Line Alerts

Where labs will stumble: standards drift, fragile revenue plumbing, middleware blind spots, and untested safety protocols

Laboratory IT is entering a decade where survival depends on interoperability discipline and revenue continuity as much as on uptime. The winners will be the labs that architect for adaptability—modular, standards-aligned, and cloud-ready.” – Black Book Research